diff --git a/Marlin/src/pins/mega/env_validate.h b/Marlin/src/pins/mega/env_validate.h
index fe4a39a612..97c52d4e5e 100644
--- a/Marlin/src/pins/mega/env_validate.h
+++ b/Marlin/src/pins/mega/env_validate.h
@@ -21,10 +21,12 @@
  */
 #pragma once
 
-#if ENABLED(ALLOW_MEGA1280) && NOT_TARGET(__AVR_ATmega1280__, __AVR_ATmega2560__)
-  #error "Oops! Select 'Arduino/Genuino Mega or Mega 2560 or 1280' in 'Tools > Board.'"
-#elif NOT_TARGET(__AVR_ATmega2560__)
-  #error "Oops! Select 'Arduino/Genuino Mega or Mega 2560' in 'Tools > Board.'"
+#if NOT_TARGET(__AVR_ATmega2560__)
+  #if DISABLED(ALLOW_MEGA1280)
+    #error "Oops! Select 'Arduino/Genuino Mega or Mega 2560' in 'Tools > Board.'"
+  #elif NOT_TARGET(__AVR_ATmega1280__)
+    #error "Oops! Select 'Arduino/Genuino Mega or Mega 2560 or 1280' in 'Tools > Board.'"
+  #endif
 #endif
 
 #undef ALLOW_MEGA1280