diff --git a/Marlin/src/core/boards.h b/Marlin/src/core/boards.h
index 7f0a99dca3..172cdd6b5a 100644
--- a/Marlin/src/core/boards.h
+++ b/Marlin/src/core/boards.h
@@ -330,10 +330,11 @@
#define BOARD_CREALITY_V4 4037 // Creality v4.x (STM32F103RE)
#define BOARD_CREALITY_V427 4038 // Creality v4.2.7 (STM32F103RE)
#define BOARD_CREALITY_V452 4039 // Creality v4.5.2 (STM32F103RE)
-#define BOARD_TRIGORILLA_PRO 4040 // Trigorilla Pro (STM32F103ZET6)
-#define BOARD_FLY_MINI 4041 // FLY MINI (STM32F103RCT6)
-#define BOARD_FLSUN_HISPEED 4042 // FLSUN HiSpeedV1 (STM32F103VET6)
-#define BOARD_BEAST 4043 // STM32F103RET6 Libmaple-based controller
+#define BOARD_CREALITY_V453 4040 // Creality v4.5.3 (STM32F103RE)
+#define BOARD_TRIGORILLA_PRO 4041 // Trigorilla Pro (STM32F103ZET6)
+#define BOARD_FLY_MINI 4042 // FLY MINI (STM32F103RCT6)
+#define BOARD_FLSUN_HISPEED 4043 // FLSUN HiSpeedV1 (STM32F103VET6)
+#define BOARD_BEAST 4044 // STM32F103RET6 Libmaple-based controller
//
// ARM Cortex-M4F
diff --git a/Marlin/src/pins/pins.h b/Marlin/src/pins/pins.h
index c9f6f7b3b3..52e6d26b14 100644
--- a/Marlin/src/pins/pins.h
+++ b/Marlin/src/pins/pins.h
@@ -532,6 +532,8 @@
#include "stm32f1/pins_CREALITY_V427.h" // STM32F1 env:STM32F103RET6_creality
#elif MB(CREALITY_V452)
#include "stm32f1/pins_CREALITY_V452.h" // STM32F1 env:STM32F103RET6_creality
+#elif MB(CREALITY_V453)
+ #include "stm32f1/pins_CREALITY_V453.h" // STM32F1 env:STM32F103RET6_creality
#elif MB(TRIGORILLA_PRO)
#include "stm32f1/pins_TRIGORILLA_PRO.h" // STM32F1 env:trigorilla_pro
#elif MB(FLY_MINI)
diff --git a/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h b/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h
index f65e1d5474..35eea1da78 100644
--- a/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h
+++ b/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h
@@ -24,97 +24,15 @@
* Creality v4.5.2 (STM32F103RET6) board pin assignments
*/
-#if NOT_TARGET(__STM32F1__)
- #error "Oops! Select an STM32F1 board in 'Tools > Board.'"
-#elif HOTENDS > 1 || E_STEPPERS > 1
- #error "CREALITY_V452 supports up to 1 hotends / E-steppers. Comment out this line to continue."
+#if HOTENDS > 1 || E_STEPPERS > 1
+ #error "Creality v4.5.2 only supports one hotend / E-stepper. Comment out this line to continue."
#endif
#define BOARD_NAME "Creality v4.5.2"
-#define DEFAULT_MACHINE_NAME "Creality3D"
-//
-// Release PB4 (Z_STEP_PIN) from JTAG NRST role
-//
-#define DISABLE_DEBUG
-
-#define BOARD_NO_NATIVE_USB
-
-//
-// EEPROM
-//
-#if NO_EEPROM_SELECTED
- #define IIC_BL24CXX_EEPROM // EEPROM on I2C-0
- //#define SDCARD_EEPROM_EMULATION
-#endif
-
-#if ENABLED(IIC_BL24CXX_EEPROM)
- #define IIC_EEPROM_SDA PA11
- #define IIC_EEPROM_SCL PA12
- #define MARLIN_EEPROM_SIZE 0x800 // 2Kb (24C16)
-#elif ENABLED(SDCARD_EEPROM_EMULATION)
- #define MARLIN_EEPROM_SIZE 0x800 // 2Kb
-#endif
-
-//
-// Limit Switches
-//
-#define X_STOP_PIN PC4
-#define Y_STOP_PIN PC5
-#define Z_STOP_PIN PA4
-
-#define FIL_RUNOUT_PIN PA7
-
-//
-// Probe
-//
-#define PROBE_TARE_PIN PA5
-#define PROBE_ENABLE_PIN PC6 // Optoswitch to Enable Z Probe
-
-//
-// Steppers
-//
-#define X_ENABLE_PIN PC3
-#define X_STEP_PIN PB8
-#define X_DIR_PIN PB7
-
-#define Y_ENABLE_PIN PC3
-#define Y_STEP_PIN PB6
-#define Y_DIR_PIN PB5
-
-#define Z_ENABLE_PIN PC3
-#define Z_STEP_PIN PB4
-#define Z_DIR_PIN PB3
-
-#define E0_ENABLE_PIN PC3
-#define E0_STEP_PIN PC2
-#define E0_DIR_PIN PB9
-
-//
-// Temperature Sensors
-//
-#define TEMP_0_PIN PB1 // TH1
-#define TEMP_BED_PIN PB0 // TB1
-
-//
-// Heaters / Fans
-//
#define HEATER_0_PIN PA1 // HEATER1
#define HEATER_BED_PIN PA2 // HOT BED
-
#define FAN_PIN PA0 // FAN
-#define FAN_SOFT_PWM
-
-//
-// SD Card
-//
-#define SD_DETECT_PIN PC7
-#define NO_SD_HOST_DRIVE // SD is only seen by the printer
-
-#define SDIO_SUPPORT // Extra added by Creality
-#define SDIO_CLOCK 6000000 // In original source code overridden by Creality in sdio.h
+#define PROBE_ENABLE_PIN PC6 // Optoswitch to Enable Z Probe
-//
-// Misc. Functions
-//
-#define CASE_LIGHT_PIN PA6
+#include "pins_CREALITY_V45x.h"
diff --git a/Marlin/src/pins/stm32f1/pins_CREALITY_V453.h b/Marlin/src/pins/stm32f1/pins_CREALITY_V453.h
new file mode 100644
index 0000000000..836e5a91f1
--- /dev/null
+++ b/Marlin/src/pins/stm32f1/pins_CREALITY_V453.h
@@ -0,0 +1,38 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (c) 2020 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (c) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program. If not, see .
+ *
+ */
+
+/**
+ * Creality v4.5.3 (STM32F103RET6) board pin assignments
+ */
+
+#if HOTENDS > 1 || E_STEPPERS > 1
+ #error "Creality v4.5.3 only supports one hotend / E-stepper. Comment out this line to continue."
+#endif
+
+#define BOARD_NAME "Creality v4.5.3"
+
+#define HEATER_0_PIN PB14 // HEATER1
+#define HEATER_BED_PIN PB13 // HOT BED
+#define FAN_PIN PB15 // FAN
+#define PROBE_ENABLE_PIN PB2 // Optoswitch to Enable Z Probe
+
+#include "pins_CREALITY_V45x.h"
diff --git a/Marlin/src/pins/stm32f1/pins_CREALITY_V45x.h b/Marlin/src/pins/stm32f1/pins_CREALITY_V45x.h
new file mode 100644
index 0000000000..f2be289530
--- /dev/null
+++ b/Marlin/src/pins/stm32f1/pins_CREALITY_V45x.h
@@ -0,0 +1,113 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (c) 2020 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (c) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program. If not, see .
+ *
+ */
+
+/**
+ * Creality v4.5.2 and v4.5.3 (STM32F103RET6) board pin assignments
+ */
+
+#if NOT_TARGET(__STM32F1__)
+ #error "Oops! Select an STM32F1 board in 'Tools > Board.'"
+#endif
+
+#define DEFAULT_MACHINE_NAME "Creality3D"
+
+//
+// Release PB4 (Z_STEP_PIN) from JTAG NRST role
+//
+#define DISABLE_DEBUG
+
+#define BOARD_NO_NATIVE_USB
+
+//
+// EEPROM
+//
+#if NO_EEPROM_SELECTED
+ #define IIC_BL24CXX_EEPROM // EEPROM on I2C-0
+ //#define SDCARD_EEPROM_EMULATION
+#endif
+
+#if ENABLED(IIC_BL24CXX_EEPROM)
+ #define IIC_EEPROM_SDA PA11
+ #define IIC_EEPROM_SCL PA12
+ #define MARLIN_EEPROM_SIZE 0x800 // 2Kb (24C16)
+#elif ENABLED(SDCARD_EEPROM_EMULATION)
+ #define MARLIN_EEPROM_SIZE 0x800 // 2Kb
+#endif
+
+//
+// Limit Switches
+//
+#define X_STOP_PIN PC4
+#define Y_STOP_PIN PC5
+#define Z_STOP_PIN PA4
+
+#define FIL_RUNOUT_PIN PA7
+
+//
+// Probe
+//
+#define PROBE_TARE_PIN PA5
+
+//
+// Steppers
+//
+#define X_ENABLE_PIN PC3
+#define X_STEP_PIN PB8
+#define X_DIR_PIN PB7
+
+#define Y_ENABLE_PIN PC3
+#define Y_STEP_PIN PB6
+#define Y_DIR_PIN PB5
+
+#define Z_ENABLE_PIN PC3
+#define Z_STEP_PIN PB4
+#define Z_DIR_PIN PB3
+
+#define E0_ENABLE_PIN PC3
+#define E0_STEP_PIN PC2
+#define E0_DIR_PIN PB9
+
+//
+// Temperature Sensors
+//
+#define TEMP_0_PIN PB1 // TH1
+#define TEMP_BED_PIN PB0 // TB1
+
+//
+// Heaters / Fans
+//
+
+#define FAN_SOFT_PWM
+
+//
+// SD Card
+//
+#define SD_DETECT_PIN PC7
+#define NO_SD_HOST_DRIVE // SD is only seen by the printer
+
+#define SDIO_SUPPORT // Extra added by Creality
+#define SDIO_CLOCK 6000000 // In original source code overridden by Creality in sdio.h
+
+//
+// Misc. Functions
+//
+#define CASE_LIGHT_PIN PA6