diff --git a/Marlin/SanityCheck.h b/Marlin/SanityCheck.h
index 7c2526bfd2..41ce24382f 100644
--- a/Marlin/SanityCheck.h
+++ b/Marlin/SanityCheck.h
@@ -722,6 +722,13 @@
   #error "TEMP_SENSOR_1 is required with TEMP_SENSOR_1_AS_REDUNDANT."
 #endif
 
+/**
+ * Temperature status LEDs
+ */
+#if ENABLED(TEMP_STAT_LEDS) && !(PIN_EXISTS(STAT_LED_RED) && PIN_EXISTS(STAT_LED_BLUE))
+  #error "TEMP_STAT_LEDS requires STAT_LED_RED_PIN and STAT_LED_BLUE_PIN."
+#endif
+
 /**
  * Basic 2-nozzle duplication mode
  */