diff --git a/Marlin/src/feature/bedlevel/ubl/ubl_G29.cpp b/Marlin/src/feature/bedlevel/ubl/ubl_G29.cpp
index d451f7246f..86a08afbff 100644
--- a/Marlin/src/feature/bedlevel/ubl/ubl_G29.cpp
+++ b/Marlin/src/feature/bedlevel/ubl/ubl_G29.cpp
@@ -38,7 +38,7 @@
   #include "../../../gcode/gcode.h"
   #include "../../../libs/least_squares_fit.h"
 
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #include "../../../module/tool_change.h"
   #endif
 
diff --git a/Marlin/src/feature/powerloss.cpp b/Marlin/src/feature/powerloss.cpp
index 37d82eec6a..77d0047a5c 100644
--- a/Marlin/src/feature/powerloss.cpp
+++ b/Marlin/src/feature/powerloss.cpp
@@ -366,11 +366,11 @@ void PrintJobRecovery::resume() {
   #endif
 
   // Restore all hotend temperatures
-  #if HOTENDS
+  #if HAS_HOTEND
     HOTEND_LOOP() {
       const int16_t et = info.target_temperature[e];
       if (et) {
-        #if HOTENDS > 1
+        #if HAS_MULTI_HOTEND
           sprintf_P(cmd, PSTR("T%i"), e);
           gcode.process_subcommands_now(cmd);
         #endif
@@ -517,7 +517,7 @@ void PrintJobRecovery::resume() {
           DEBUG_ECHOLNPAIR("active_extruder: ", int(info.active_extruder));
         #endif
 
-        #if HOTENDS
+        #if HAS_HOTEND
           DEBUG_ECHOPGM("target_temperature: ");
           HOTEND_LOOP() {
             DEBUG_ECHO(info.target_temperature[e]);
diff --git a/Marlin/src/feature/powerloss.h b/Marlin/src/feature/powerloss.h
index 0496560785..34a26b6eb9 100644
--- a/Marlin/src/feature/powerloss.h
+++ b/Marlin/src/feature/powerloss.h
@@ -68,7 +68,7 @@ typedef struct {
     #endif
   #endif
 
-  #if HOTENDS
+  #if HAS_HOTEND
     int16_t target_temperature[HOTENDS];
   #endif
 
diff --git a/Marlin/src/gcode/bedlevel/abl/G29.cpp b/Marlin/src/gcode/bedlevel/abl/G29.cpp
index de69545983..f316b4a7a1 100644
--- a/Marlin/src/gcode/bedlevel/abl/G29.cpp
+++ b/Marlin/src/gcode/bedlevel/abl/G29.cpp
@@ -60,7 +60,7 @@
   #include "../../../lcd/extui/ui_api.h"
 #endif
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #include "../../../module/tool_change.h"
 #endif
 
@@ -283,7 +283,7 @@ G29_TYPE GcodeSuite::G29() {
    */
   if (!g29_in_progress) {
 
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       if (active_extruder != 0) tool_change(0);
     #endif
 
diff --git a/Marlin/src/gcode/calibrate/G28.cpp b/Marlin/src/gcode/calibrate/G28.cpp
index 3437e33942..8c699b5fd3 100644
--- a/Marlin/src/gcode/calibrate/G28.cpp
+++ b/Marlin/src/gcode/calibrate/G28.cpp
@@ -27,7 +27,7 @@
 #include "../../module/stepper.h"
 #include "../../module/endstops.h"
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #include "../../module/tool_change.h"
 #endif
 
@@ -285,7 +285,7 @@ void GcodeSuite::G28() {
   #endif
 
   // Always home with tool 0 active
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if DISABLED(DELTA) || ENABLED(DELTA_HOME_TO_SAFE_ZONE)
       const uint8_t old_tool_index = active_extruder;
     #endif
@@ -474,7 +474,7 @@ void GcodeSuite::G28() {
   restore_feedrate_and_scaling();
 
   // Restore the active tool after homing
-  #if HOTENDS > 1 && (DISABLED(DELTA) || ENABLED(DELTA_HOME_TO_SAFE_ZONE))
+  #if HAS_MULTI_HOTEND && (DISABLED(DELTA) || ENABLED(DELTA_HOME_TO_SAFE_ZONE))
     tool_change(old_tool_index, NONE(PARKING_EXTRUDER, DUAL_X_CARRIAGE));   // Do move if one of these
   #endif
 
diff --git a/Marlin/src/gcode/calibrate/G33.cpp b/Marlin/src/gcode/calibrate/G33.cpp
index ac2cdf7d4d..6f0f8a5562 100644
--- a/Marlin/src/gcode/calibrate/G33.cpp
+++ b/Marlin/src/gcode/calibrate/G33.cpp
@@ -35,7 +35,7 @@
   #include "../../module/probe.h"
 #endif
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #include "../../module/tool_change.h"
 #endif
 
diff --git a/Marlin/src/gcode/calibrate/G34_M422.cpp b/Marlin/src/gcode/calibrate/G34_M422.cpp
index d1b828d079..091619c6ff 100644
--- a/Marlin/src/gcode/calibrate/G34_M422.cpp
+++ b/Marlin/src/gcode/calibrate/G34_M422.cpp
@@ -32,7 +32,7 @@
 #include "../../module/motion.h"
 #include "../../module/probe.h"
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #include "../../module/tool_change.h"
 #endif
 
@@ -124,7 +124,7 @@ void GcodeSuite::G34() {
     #endif
 
     // Always home with tool 0 active
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       const uint8_t old_tool_index = active_extruder;
       tool_change(0, true);
     #endif
@@ -386,7 +386,7 @@ void GcodeSuite::G34() {
     #endif
 
     // Restore the active tool after homing
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       tool_change(old_tool_index, DISABLED(PARKING_EXTRUDER)); // Fetch previous tool for parking extruder
     #endif
 
diff --git a/Marlin/src/gcode/calibrate/G425.cpp b/Marlin/src/gcode/calibrate/G425.cpp
index 6ac3c70c48..b9dcc8f284 100644
--- a/Marlin/src/gcode/calibrate/G425.cpp
+++ b/Marlin/src/gcode/calibrate/G425.cpp
@@ -126,7 +126,7 @@ inline void park_above_object(measurements_t &m, const float uncertainty) {
   calibration_move();
 }
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   inline void set_nozzle(measurements_t &m, const uint8_t extruder) {
     if (extruder != active_extruder) {
       park_above_object(m, CALIBRATION_MEASUREMENT_UNKNOWN);
@@ -505,7 +505,7 @@ inline void calibrate_toolhead(measurements_t &m, const float uncertainty, const
   TEMPORARY_BACKLASH_CORRECTION(all_on);
   TEMPORARY_BACKLASH_SMOOTHING(0.0f);
 
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     set_nozzle(m, extruder);
   #else
     UNUSED(extruder);
@@ -548,7 +548,7 @@ inline void calibrate_all_toolheads(measurements_t &m, const float uncertainty)
     normalize_hotend_offsets();
   #endif
 
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     set_nozzle(m, 0);
   #endif
 }
@@ -582,7 +582,7 @@ inline void calibrate_all() {
   #endif
 
   // Cycle the toolheads so the servos settle into their "natural" positions
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     HOTEND_LOOP() set_nozzle(m, e);
   #endif
 
diff --git a/Marlin/src/inc/Conditionals_LCD.h b/Marlin/src/inc/Conditionals_LCD.h
index 7adb08a4e6..ac44e832d6 100644
--- a/Marlin/src/inc/Conditionals_LCD.h
+++ b/Marlin/src/inc/Conditionals_LCD.h
@@ -466,6 +466,14 @@
   #define E_MANUAL EXTRUDERS
 #endif
 
+#if HOTENDS
+  #define HAS_HOTEND 1
+  #if HOTENDS > 1
+    #define HAS_MULTI_HOTEND 1
+    #define HAS_HOTEND_OFFSET 1
+  #endif
+#endif
+
 // Helper macros for extruder and hotend arrays
 #define HOTEND_LOOP() for (int8_t e = 0; e < HOTENDS; e++)
 #define ARRAY_BY_EXTRUDERS(V...) ARRAY_N(EXTRUDERS, V)
@@ -481,10 +489,6 @@
   #define SWITCHING_NOZZLE_TWO_SERVOS 1
 #endif
 
-#if HOTENDS > 1
-  #define HAS_HOTEND_OFFSET 1
-#endif
-
 /**
  * Default hotend offsets, if not defined
  */
diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index ee41c4af67..48490b75a5 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -386,7 +386,7 @@
 #endif
 
 #if !defined(PSU_POWERUP_DELAY) && ENABLED(PSU_CONTROL)
-  #define PSU_POWERUP_DELAY 100
+  #define PSU_POWERUP_DELAY 250
 #endif
 
 /**
@@ -1255,94 +1255,238 @@
  */
 
 // Steppers
-#define HAS_X_ENABLE      (PIN_EXISTS(X_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(X)))
-#define HAS_X_DIR         (PIN_EXISTS(X_DIR))
-#define HAS_X_STEP        (PIN_EXISTS(X_STEP))
-#define HAS_X_MICROSTEPS  (PIN_EXISTS(X_MS1))
-
-#define HAS_X2_ENABLE     (PIN_EXISTS(X2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(X2)))
-#define HAS_X2_DIR        (PIN_EXISTS(X2_DIR))
-#define HAS_X2_STEP       (PIN_EXISTS(X2_STEP))
-#define HAS_X2_MICROSTEPS (PIN_EXISTS(X2_MS1))
-
-#define HAS_Y_ENABLE      (PIN_EXISTS(Y_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Y)))
-#define HAS_Y_DIR         (PIN_EXISTS(Y_DIR))
-#define HAS_Y_STEP        (PIN_EXISTS(Y_STEP))
-#define HAS_Y_MICROSTEPS  (PIN_EXISTS(Y_MS1))
-
-#define HAS_Y2_ENABLE     (PIN_EXISTS(Y2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Y2)))
-#define HAS_Y2_DIR        (PIN_EXISTS(Y2_DIR))
-#define HAS_Y2_STEP       (PIN_EXISTS(Y2_STEP))
-#define HAS_Y2_MICROSTEPS (PIN_EXISTS(Y2_MS1))
-
-#define HAS_Z_ENABLE      (PIN_EXISTS(Z_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z)))
-#define HAS_Z_DIR         (PIN_EXISTS(Z_DIR))
-#define HAS_Z_STEP        (PIN_EXISTS(Z_STEP))
-#define HAS_Z_MICROSTEPS  (PIN_EXISTS(Z_MS1))
-
-#define HAS_Z2_ENABLE     (PIN_EXISTS(Z2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z2)))
-#define HAS_Z2_DIR        (PIN_EXISTS(Z2_DIR))
-#define HAS_Z2_STEP       (PIN_EXISTS(Z2_STEP))
-#define HAS_Z2_MICROSTEPS (PIN_EXISTS(Z2_MS1))
-
-#define HAS_Z3_ENABLE     (PIN_EXISTS(Z3_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z3)))
-#define HAS_Z3_DIR        (PIN_EXISTS(Z3_DIR))
-#define HAS_Z3_STEP       (PIN_EXISTS(Z3_STEP))
-#define HAS_Z3_MICROSTEPS (PIN_EXISTS(Z3_MS1))
-
-#define HAS_Z4_ENABLE     (PIN_EXISTS(Z4_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z4)))
-#define HAS_Z4_DIR        (PIN_EXISTS(Z4_DIR))
-#define HAS_Z4_STEP       (PIN_EXISTS(Z4_STEP))
-#define HAS_Z4_MICROSTEPS (PIN_EXISTS(Z4_MS1))
+#if PIN_EXISTS(X_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(X))
+  #define HAS_X_ENABLE 1
+#endif
+#if PIN_EXISTS(X_DIR)
+  #define HAS_X_DIR 1
+#endif
+#if PIN_EXISTS(X_STEP)
+  #define HAS_X_STEP 1
+#endif
+#if PIN_EXISTS(X_MS1)
+  #define HAS_X_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(X2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(X2))
+  #define HAS_X2_ENABLE 1
+#endif
+#if PIN_EXISTS(X2_DIR)
+  #define HAS_X2_DIR 1
+#endif
+#if PIN_EXISTS(X2_STEP)
+  #define HAS_X2_STEP 1
+#endif
+#if PIN_EXISTS(X2_MS1)
+  #define HAS_X2_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Y_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Y))
+  #define HAS_Y_ENABLE 1
+#endif
+#if PIN_EXISTS(Y_DIR)
+  #define HAS_Y_DIR 1
+#endif
+#if PIN_EXISTS(Y_STEP)
+  #define HAS_Y_STEP 1
+#endif
+#if PIN_EXISTS(Y_MS1)
+  #define HAS_Y_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Y2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Y2))
+  #define HAS_Y2_ENABLE 1
+#endif
+#if PIN_EXISTS(Y2_DIR)
+  #define HAS_Y2_DIR 1
+#endif
+#if PIN_EXISTS(Y2_STEP)
+  #define HAS_Y2_STEP 1
+#endif
+#if PIN_EXISTS(Y2_MS1)
+  #define HAS_Y2_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Z_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z))
+  #define HAS_Z_ENABLE 1
+#endif
+#if PIN_EXISTS(Z_DIR)
+  #define HAS_Z_DIR 1
+#endif
+#if PIN_EXISTS(Z_STEP)
+  #define HAS_Z_STEP 1
+#endif
+#if PIN_EXISTS(Z_MS1)
+  #define HAS_Z_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Z2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z2))
+  #define HAS_Z2_ENABLE 1
+#endif
+#if PIN_EXISTS(Z2_DIR)
+  #define HAS_Z2_DIR 1
+#endif
+#if PIN_EXISTS(Z2_STEP)
+  #define HAS_Z2_STEP 1
+#endif
+#if PIN_EXISTS(Z2_MS1)
+  #define HAS_Z2_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Z3_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z3))
+  #define HAS_Z3_ENABLE 1
+#endif
+#if PIN_EXISTS(Z3_DIR)
+  #define HAS_Z3_DIR 1
+#endif
+#if PIN_EXISTS(Z3_STEP)
+  #define HAS_Z3_STEP 1
+#endif
+#if PIN_EXISTS(Z3_MS1)
+  #define HAS_Z3_MICROSTEPS 1
+#endif
+
+#if PIN_EXISTS(Z4_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(Z4))
+  #define HAS_Z4_ENABLE 1
+#endif
+#if PIN_EXISTS(Z4_DIR)
+  #define HAS_Z4_DIR 1
+#endif
+#if PIN_EXISTS(Z4_STEP)
+  #define HAS_Z4_STEP 1
+#endif
+#if PIN_EXISTS(Z4_MS1)
+  #define HAS_Z4_MICROSTEPS 1
+#endif
 
 // Extruder steppers and solenoids
-#define HAS_E0_ENABLE     (PIN_EXISTS(E0_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E0)))
-#define HAS_E0_DIR        (PIN_EXISTS(E0_DIR))
-#define HAS_E0_STEP       (PIN_EXISTS(E0_STEP))
-#define HAS_E0_MICROSTEPS (PIN_EXISTS(E0_MS1))
-#define HAS_SOLENOID_0    (PIN_EXISTS(SOL0))
-
-#define HAS_E1_ENABLE     (PIN_EXISTS(E1_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E1)))
-#define HAS_E1_DIR        (PIN_EXISTS(E1_DIR))
-#define HAS_E1_STEP       (PIN_EXISTS(E1_STEP))
-#define HAS_E1_MICROSTEPS (PIN_EXISTS(E1_MS1))
-#define HAS_SOLENOID_1    (PIN_EXISTS(SOL1))
-
-#define HAS_E2_ENABLE     (PIN_EXISTS(E2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E2)))
-#define HAS_E2_DIR        (PIN_EXISTS(E2_DIR))
-#define HAS_E2_STEP       (PIN_EXISTS(E2_STEP))
-#define HAS_E2_MICROSTEPS (PIN_EXISTS(E2_MS1))
-#define HAS_SOLENOID_2    (PIN_EXISTS(SOL2))
-
-#define HAS_E3_ENABLE     (PIN_EXISTS(E3_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E3)))
-#define HAS_E3_DIR        (PIN_EXISTS(E3_DIR))
-#define HAS_E3_STEP       (PIN_EXISTS(E3_STEP))
-#define HAS_E3_MICROSTEPS (PIN_EXISTS(E3_MS1))
-#define HAS_SOLENOID_3    (PIN_EXISTS(SOL3))
-
-#define HAS_E4_ENABLE     (PIN_EXISTS(E4_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E4)))
-#define HAS_E4_DIR        (PIN_EXISTS(E4_DIR))
-#define HAS_E4_STEP       (PIN_EXISTS(E4_STEP))
-#define HAS_E4_MICROSTEPS (PIN_EXISTS(E4_MS1))
-#define HAS_SOLENOID_4    (PIN_EXISTS(SOL4))
-
-#define HAS_E5_ENABLE     (PIN_EXISTS(E5_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E5)))
-#define HAS_E5_DIR        (PIN_EXISTS(E5_DIR))
-#define HAS_E5_STEP       (PIN_EXISTS(E5_STEP))
-#define HAS_E5_MICROSTEPS (PIN_EXISTS(E5_MS1))
-#define HAS_SOLENOID_5    (PIN_EXISTS(SOL5))
-
-#define HAS_E6_ENABLE     (PIN_EXISTS(E6_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E6)))
-#define HAS_E6_DIR        (PIN_EXISTS(E6_DIR))
-#define HAS_E6_STEP       (PIN_EXISTS(E6_STEP))
-#define HAS_E6_MICROSTEPS (PIN_EXISTS(E6_MS1))
-#define HAS_SOLENOID_6    (PIN_EXISTS(SOL6))
-
-#define HAS_E7_ENABLE     (PIN_EXISTS(E7_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E7)))
-#define HAS_E7_DIR        (PIN_EXISTS(E7_DIR))
-#define HAS_E7_STEP       (PIN_EXISTS(E7_STEP))
-#define HAS_E7_MICROSTEPS (PIN_EXISTS(E7_MS1))
-#define HAS_SOLENOID_7    (PIN_EXISTS(SOL7))
+#if PIN_EXISTS(E0_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E0))
+  #define HAS_E0_ENABLE 1
+#endif
+#if PIN_EXISTS(E0_DIR)
+  #define HAS_E0_DIR 1
+#endif
+#if PIN_EXISTS(E0_STEP)
+  #define HAS_E0_STEP 1
+#endif
+#if PIN_EXISTS(E0_MS1)
+  #define HAS_E0_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL0)
+  #define HAS_SOLENOID_0 1
+#endif
+
+#if PIN_EXISTS(E1_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E1))
+  #define HAS_E1_ENABLE 1
+#endif
+#if PIN_EXISTS(E1_DIR)
+  #define HAS_E1_DIR 1
+#endif
+#if PIN_EXISTS(E1_STEP)
+  #define HAS_E1_STEP 1
+#endif
+#if PIN_EXISTS(E1_MS1)
+  #define HAS_E1_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL1)
+  #define HAS_SOLENOID_1 1
+#endif
+
+#if PIN_EXISTS(E2_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E2))
+  #define HAS_E2_ENABLE 1
+#endif
+#if PIN_EXISTS(E2_DIR)
+  #define HAS_E2_DIR 1
+#endif
+#if PIN_EXISTS(E2_STEP)
+  #define HAS_E2_STEP 1
+#endif
+#if PIN_EXISTS(E2_MS1)
+  #define HAS_E2_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL2)
+  #define HAS_SOLENOID_2 1
+#endif
+
+#if PIN_EXISTS(E3_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E3))
+  #define HAS_E3_ENABLE 1
+#endif
+#if PIN_EXISTS(E3_DIR)
+  #define HAS_E3_DIR 1
+#endif
+#if PIN_EXISTS(E3_STEP)
+  #define HAS_E3_STEP 1
+#endif
+#if PIN_EXISTS(E3_MS1)
+  #define HAS_E3_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL3)
+  #define HAS_SOLENOID_3 1
+#endif
+
+#if PIN_EXISTS(E4_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E4))
+  #define HAS_E4_ENABLE 1
+#endif
+#if PIN_EXISTS(E4_DIR)
+  #define HAS_E4_DIR 1
+#endif
+#if PIN_EXISTS(E4_STEP)
+  #define HAS_E4_STEP 1
+#endif
+#if PIN_EXISTS(E4_MS1)
+  #define HAS_E4_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL4)
+  #define HAS_SOLENOID_4 1
+#endif
+
+#if PIN_EXISTS(E5_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E5))
+  #define HAS_E5_ENABLE 1
+#endif
+#if PIN_EXISTS(E5_DIR)
+  #define HAS_E5_DIR 1
+#endif
+#if PIN_EXISTS(E5_STEP)
+  #define HAS_E5_STEP 1
+#endif
+#if PIN_EXISTS(E5_MS1)
+  #define HAS_E5_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL5)
+  #define HAS_SOLENOID_5 1
+#endif
+
+#if PIN_EXISTS(E6_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E6))
+  #define HAS_E6_ENABLE 1
+#endif
+#if PIN_EXISTS(E6_DIR)
+  #define HAS_E6_DIR 1
+#endif
+#if PIN_EXISTS(E6_STEP)
+  #define HAS_E6_STEP 1
+#endif
+#if PIN_EXISTS(E6_MS1)
+  #define HAS_E6_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL6)
+  #define HAS_SOLENOID_6 1
+#endif
+
+#if PIN_EXISTS(E7_ENABLE) || (ENABLED(SOFTWARE_DRIVER_ENABLE) && AXIS_IS_TMC(E7))
+  #define HAS_E7_ENABLE 1
+#endif
+#if PIN_EXISTS(E7_DIR)
+  #define HAS_E7_DIR 1
+#endif
+#if PIN_EXISTS(E7_STEP)
+  #define HAS_E7_STEP 1
+#endif
+#if PIN_EXISTS(E7_MS1)
+  #define HAS_E7_MICROSTEPS 1
+#endif
+#if PIN_EXISTS(SOL7)
+  #define HAS_SOLENOID_7 1
+#endif
 
 // Trinamic Stepper Drivers
 #if HAS_TRINAMIC_CONFIG
@@ -1405,62 +1549,146 @@
 #define IS_Z4_ENDSTOP(A,M) (ENABLED(Z_MULTI_ENDSTOPS) && NUM_Z_STEPPER_DRIVERS >= 4 && Z4_USE_ENDSTOP == _##A##M##_)
 
 #define _HAS_STOP(A,M) (PIN_EXISTS(A##_##M) && !IS_PROBE_PIN(A,M) && !IS_X2_ENDSTOP(A,M) && !IS_Y2_ENDSTOP(A,M) && !IS_Z2_ENDSTOP(A,M) && !IS_Z3_ENDSTOP(A,M) && !IS_Z4_ENDSTOP(A,M))
-#define HAS_X_MIN _HAS_STOP(X,MIN)
-#define HAS_X_MAX _HAS_STOP(X,MAX)
-#define HAS_Y_MIN _HAS_STOP(Y,MIN)
-#define HAS_Y_MAX _HAS_STOP(Y,MAX)
-#define HAS_Z_MIN _HAS_STOP(Z,MIN)
-#define HAS_Z_MAX _HAS_STOP(Z,MAX)
-#define HAS_X2_MIN (PIN_EXISTS(X2_MIN))
-#define HAS_X2_MAX (PIN_EXISTS(X2_MAX))
-#define HAS_Y2_MIN (PIN_EXISTS(Y2_MIN))
-#define HAS_Y2_MAX (PIN_EXISTS(Y2_MAX))
-#define HAS_Z2_MIN (PIN_EXISTS(Z2_MIN))
-#define HAS_Z2_MAX (PIN_EXISTS(Z2_MAX))
-#define HAS_Z3_MIN (PIN_EXISTS(Z3_MIN))
-#define HAS_Z3_MAX (PIN_EXISTS(Z3_MAX))
-#define HAS_Z4_MIN (PIN_EXISTS(Z4_MIN))
-#define HAS_Z4_MAX (PIN_EXISTS(Z4_MAX))
-#define HAS_Z_MIN_PROBE_PIN (HAS_CUSTOM_PROBE_PIN && PIN_EXISTS(Z_MIN_PROBE))
+#if _HAS_STOP(X,MIN)
+  #define HAS_X_MIN 1
+#endif
+#if _HAS_STOP(X,MAX)
+  #define HAS_X_MAX 1
+#endif
+#if _HAS_STOP(Y,MIN)
+  #define HAS_Y_MIN 1
+#endif
+#if _HAS_STOP(Y,MAX)
+  #define HAS_Y_MAX 1
+#endif
+#if _HAS_STOP(Z,MIN)
+  #define HAS_Z_MIN 1
+#endif
+#if _HAS_STOP(Z,MAX)
+  #define HAS_Z_MAX 1
+#endif
+#if PIN_EXISTS(X2_MIN)
+  #define HAS_X2_MIN 1
+#endif
+#if PIN_EXISTS(X2_MAX)
+  #define HAS_X2_MAX 1
+#endif
+#if PIN_EXISTS(Y2_MIN)
+  #define HAS_Y2_MIN 1
+#endif
+#if PIN_EXISTS(Y2_MAX)
+  #define HAS_Y2_MAX 1
+#endif
+#if PIN_EXISTS(Z2_MIN)
+  #define HAS_Z2_MIN 1
+#endif
+#if PIN_EXISTS(Z2_MAX)
+  #define HAS_Z2_MAX 1
+#endif
+#if PIN_EXISTS(Z3_MIN)
+  #define HAS_Z3_MIN 1
+#endif
+#if PIN_EXISTS(Z3_MAX)
+  #define HAS_Z3_MAX 1
+#endif
+#if PIN_EXISTS(Z4_MIN)
+  #define HAS_Z4_MIN 1
+#endif
+#if PIN_EXISTS(Z4_MAX)
+  #define HAS_Z4_MAX 1
+#endif
+#if HAS_CUSTOM_PROBE_PIN && PIN_EXISTS(Z_MIN_PROBE)
+  #define HAS_Z_MIN_PROBE_PIN 1
+#endif
 
 //
 // ADC Temp Sensors (Thermistor or Thermocouple with amplifier ADC interface)
 //
 #define HAS_ADC_TEST(P) (PIN_EXISTS(TEMP_##P) && TEMP_SENSOR_##P != 0 && DISABLED(HEATER_##P##_USES_MAX6675))
-#define HAS_TEMP_ADC_0        HAS_ADC_TEST(0)
-#define HAS_TEMP_ADC_1        HAS_ADC_TEST(1)
-#define HAS_TEMP_ADC_2        HAS_ADC_TEST(2)
-#define HAS_TEMP_ADC_3        HAS_ADC_TEST(3)
-#define HAS_TEMP_ADC_4        HAS_ADC_TEST(4)
-#define HAS_TEMP_ADC_5        HAS_ADC_TEST(5)
-#define HAS_TEMP_ADC_6        HAS_ADC_TEST(6)
-#define HAS_TEMP_ADC_7        HAS_ADC_TEST(7)
-#define HAS_TEMP_ADC_BED      HAS_ADC_TEST(BED)
-#define HAS_TEMP_ADC_PROBE    HAS_ADC_TEST(PROBE)
-#define HAS_TEMP_ADC_CHAMBER  HAS_ADC_TEST(CHAMBER)
-
-#define HAS_TEMP_HOTEND   ((HAS_TEMP_ADC_0 || ENABLED(HEATER_0_USES_MAX6675)) && HOTENDS)
+#if HAS_ADC_TEST(0)
+  #define HAS_TEMP_ADC_0 1
+#endif
+#if HAS_ADC_TEST(1)
+  #define HAS_TEMP_ADC_1 1
+#endif
+#if HAS_ADC_TEST(2)
+  #define HAS_TEMP_ADC_2 1
+#endif
+#if HAS_ADC_TEST(3)
+  #define HAS_TEMP_ADC_3 1
+#endif
+#if HAS_ADC_TEST(4)
+  #define HAS_TEMP_ADC_4 1
+#endif
+#if HAS_ADC_TEST(5)
+  #define HAS_TEMP_ADC_5 1
+#endif
+#if HAS_ADC_TEST(6)
+  #define HAS_TEMP_ADC_6 1
+#endif
+#if HAS_ADC_TEST(7)
+  #define HAS_TEMP_ADC_7 1
+#endif
+#if HAS_ADC_TEST(BED)
+  #define HAS_TEMP_ADC_BED 1
+#endif
+#if HAS_ADC_TEST(PROBE)
+  #define HAS_TEMP_ADC_PROBE 1
+#endif
+#if HAS_ADC_TEST(CHAMBER)
+  #define HAS_TEMP_ADC_CHAMBER 1
+#endif
+
+#if HOTENDS && (HAS_TEMP_ADC_0 || ENABLED(HEATER_0_USES_MAX6675))
+  #define HAS_TEMP_HOTEND 1
+#endif
 #define HAS_TEMP_BED        HAS_TEMP_ADC_BED
 #define HAS_TEMP_PROBE      HAS_TEMP_ADC_PROBE
 #define HAS_TEMP_CHAMBER    HAS_TEMP_ADC_CHAMBER
 
 #if ENABLED(JOYSTICK)
-  #define HAS_JOY_ADC_X  PIN_EXISTS(JOY_X)
-  #define HAS_JOY_ADC_Y  PIN_EXISTS(JOY_Y)
-  #define HAS_JOY_ADC_Z  PIN_EXISTS(JOY_Z)
-  #define HAS_JOY_ADC_EN PIN_EXISTS(JOY_EN)
+  #if PIN_EXISTS(JOY_X)
+    #define HAS_JOY_ADC_X 1
+#endif
+  #if PIN_EXISTS(JOY_Y)
+    #define HAS_JOY_ADC_Y 1
+#endif
+  #if PIN_EXISTS(JOY_Z)
+    #define HAS_JOY_ADC_Z 1
+#endif
+  #if PIN_EXISTS(JOY_EN)
+    #define HAS_JOY_ADC_EN 1
+#endif
 #endif
 
 // Heaters
-#define HAS_HEATER_0    (PIN_EXISTS(HEATER_0))
-#define HAS_HEATER_1    (PIN_EXISTS(HEATER_1))
-#define HAS_HEATER_2    (PIN_EXISTS(HEATER_2))
-#define HAS_HEATER_3    (PIN_EXISTS(HEATER_3))
-#define HAS_HEATER_4    (PIN_EXISTS(HEATER_4))
-#define HAS_HEATER_5    (PIN_EXISTS(HEATER_5))
-#define HAS_HEATER_6    (PIN_EXISTS(HEATER_6))
-#define HAS_HEATER_7    (PIN_EXISTS(HEATER_7))
-#define HAS_HEATER_BED  (PIN_EXISTS(HEATER_BED))
+#if PIN_EXISTS(HEATER_0)
+  #define HAS_HEATER_0 1
+#endif
+#if PIN_EXISTS(HEATER_1)
+  #define HAS_HEATER_1 1
+#endif
+#if PIN_EXISTS(HEATER_2)
+  #define HAS_HEATER_2 1
+#endif
+#if PIN_EXISTS(HEATER_3)
+  #define HAS_HEATER_3 1
+#endif
+#if PIN_EXISTS(HEATER_4)
+  #define HAS_HEATER_4 1
+#endif
+#if PIN_EXISTS(HEATER_5)
+  #define HAS_HEATER_5 1
+#endif
+#if PIN_EXISTS(HEATER_6)
+  #define HAS_HEATER_6 1
+#endif
+#if PIN_EXISTS(HEATER_7)
+  #define HAS_HEATER_7 1
+#endif
+#if PIN_EXISTS(HEATER_BED)
+  #define HAS_HEATER_BED 1
+#endif
 
 // Shorthand for common combinations
 #if HAS_TEMP_BED && HAS_HEATER_BED
@@ -1507,15 +1735,33 @@
 #endif
 
 // Auto fans
-#define HAS_AUTO_FAN_0 (HOTENDS > 0 && PIN_EXISTS(E0_AUTO_FAN))
-#define HAS_AUTO_FAN_1 (HOTENDS > 1 && PIN_EXISTS(E1_AUTO_FAN))
-#define HAS_AUTO_FAN_2 (HOTENDS > 2 && PIN_EXISTS(E2_AUTO_FAN))
-#define HAS_AUTO_FAN_3 (HOTENDS > 3 && PIN_EXISTS(E3_AUTO_FAN))
-#define HAS_AUTO_FAN_4 (HOTENDS > 4 && PIN_EXISTS(E4_AUTO_FAN))
-#define HAS_AUTO_FAN_5 (HOTENDS > 5 && PIN_EXISTS(E5_AUTO_FAN))
-#define HAS_AUTO_FAN_6 (HOTENDS > 6 && PIN_EXISTS(E6_AUTO_FAN))
-#define HAS_AUTO_FAN_7 (HOTENDS > 7 && PIN_EXISTS(E7_AUTO_FAN))
-#define HAS_AUTO_CHAMBER_FAN (HAS_TEMP_CHAMBER && PIN_EXISTS(CHAMBER_AUTO_FAN))
+#if HAS_HOTEND && PIN_EXISTS(E0_AUTO_FAN)
+  #define HAS_AUTO_FAN_0 1
+#endif
+#if HOTENDS > 1 && PIN_EXISTS(E1_AUTO_FAN)
+  #define HAS_AUTO_FAN_1 1
+#endif
+#if HOTENDS > 2 && PIN_EXISTS(E2_AUTO_FAN)
+  #define HAS_AUTO_FAN_2 1
+#endif
+#if HOTENDS > 3 && PIN_EXISTS(E3_AUTO_FAN)
+  #define HAS_AUTO_FAN_3 1
+#endif
+#if HOTENDS > 4 && PIN_EXISTS(E4_AUTO_FAN)
+  #define HAS_AUTO_FAN_4 1
+#endif
+#if HOTENDS > 5 && PIN_EXISTS(E5_AUTO_FAN)
+  #define HAS_AUTO_FAN_5 1
+#endif
+#if HOTENDS > 6 && PIN_EXISTS(E6_AUTO_FAN)
+  #define HAS_AUTO_FAN_6 1
+#endif
+#if HOTENDS > 7 && PIN_EXISTS(E7_AUTO_FAN)
+  #define HAS_AUTO_FAN_7 1
+#endif
+#if HAS_TEMP_CHAMBER && PIN_EXISTS(CHAMBER_AUTO_FAN)
+  #define HAS_AUTO_CHAMBER_FAN 1
+#endif
 
 #define HAS_AUTO_FAN (HAS_AUTO_FAN_0 || HAS_AUTO_FAN_1 || HAS_AUTO_FAN_2 || HAS_AUTO_FAN_3 || HAS_AUTO_FAN_4 || HAS_AUTO_FAN_5 || HAS_AUTO_FAN_6 || HAS_AUTO_FAN_7 || HAS_AUTO_CHAMBER_FAN)
 #define _FANOVERLAP(A,B) (A##_AUTO_FAN_PIN == E##B##_AUTO_FAN_PIN)
@@ -1535,24 +1781,52 @@
 // Other fans
 #define HAS_FAN0 (PIN_EXISTS(FAN))
 #define _HAS_FAN(P) (PIN_EXISTS(FAN##P) && CONTROLLER_FAN_PIN != FAN##P##_PIN && E0_AUTO_FAN_PIN != FAN##P##_PIN && E1_AUTO_FAN_PIN != FAN##P##_PIN && E2_AUTO_FAN_PIN != FAN##P##_PIN && E3_AUTO_FAN_PIN != FAN##P##_PIN && E4_AUTO_FAN_PIN != FAN##P##_PIN && E5_AUTO_FAN_PIN != FAN##P##_PIN && E6_AUTO_FAN_PIN != FAN##P##_PIN && E7_AUTO_FAN_PIN != FAN##P##_PIN)
-#define HAS_FAN1 _HAS_FAN(1)
-#define HAS_FAN2 _HAS_FAN(2)
-#define HAS_FAN3 _HAS_FAN(3)
-#define HAS_FAN4 _HAS_FAN(4)
-#define HAS_FAN5 _HAS_FAN(5)
-#define HAS_FAN6 _HAS_FAN(6)
-#define HAS_FAN7 _HAS_FAN(7)
-#define HAS_CONTROLLER_FAN (PIN_EXISTS(CONTROLLER_FAN))
+#if _HAS_FAN(1)
+  #define HAS_FAN1 1
+#endif
+#if _HAS_FAN(2)
+  #define HAS_FAN2 1
+#endif
+#if _HAS_FAN(3)
+  #define HAS_FAN3 1
+#endif
+#if _HAS_FAN(4)
+  #define HAS_FAN4 1
+#endif
+#if _HAS_FAN(5)
+  #define HAS_FAN5 1
+#endif
+#if _HAS_FAN(6)
+  #define HAS_FAN6 1
+#endif
+#if _HAS_FAN(7)
+  #define HAS_FAN7 1
+#endif
+#if PIN_EXISTS(CONTROLLER_FAN)
+  #define HAS_CONTROLLER_FAN 1
+#endif
 
 // Servos
-#define HAS_SERVO_0 (PIN_EXISTS(SERVO0) && NUM_SERVOS > 0)
-#define HAS_SERVO_1 (PIN_EXISTS(SERVO1) && NUM_SERVOS > 1)
-#define HAS_SERVO_2 (PIN_EXISTS(SERVO2) && NUM_SERVOS > 2)
-#define HAS_SERVO_3 (PIN_EXISTS(SERVO3) && NUM_SERVOS > 3)
-#define HAS_SERVOS  (NUM_SERVOS > 0)
+#if PIN_EXISTS(SERVO0) && NUM_SERVOS > 0
+  #define HAS_SERVO_0 1
+#endif
+#if PIN_EXISTS(SERVO1) && NUM_SERVOS > 1
+  #define HAS_SERVO_1 1
+#endif
+#if PIN_EXISTS(SERVO2) && NUM_SERVOS > 2
+  #define HAS_SERVO_2 1
+#endif
+#if PIN_EXISTS(SERVO3) && NUM_SERVOS > 3
+  #define HAS_SERVO_3 1
+#endif
+#if NUM_SERVOS > 0
+  #define HAS_SERVOS 1
+#endif
 
 // Sensors
-#define HAS_FILAMENT_WIDTH_SENSOR (PIN_EXISTS(FILWIDTH))
+#if PIN_EXISTS(FILWIDTH)
+  #define HAS_FILAMENT_WIDTH_SENSOR 1
+#endif
 
 // User Interface
 #if PIN_EXISTS(HOME)
@@ -1638,14 +1912,30 @@
     #endif
   #endif
 
-  #define HAS_MICROSTEP1 defined(MICROSTEP1)
-  #define HAS_MICROSTEP2 defined(MICROSTEP2)
-  #define HAS_MICROSTEP4 defined(MICROSTEP4)
-  #define HAS_MICROSTEP8 defined(MICROSTEP8)
-  #define HAS_MICROSTEP16 defined(MICROSTEP16)
-  #define HAS_MICROSTEP32 defined(MICROSTEP32)
-  #define HAS_MICROSTEP64 defined(MICROSTEP64)
-  #define HAS_MICROSTEP128 defined(MICROSTEP128)
+  #ifdef MICROSTEP1
+    #define HAS_MICROSTEP1 1
+  #endif
+  #ifdef MICROSTEP2
+    #define HAS_MICROSTEP2 1
+  #endif
+  #ifdef MICROSTEP4
+    #define HAS_MICROSTEP4 1
+  #endif
+  #ifdef MICROSTEP8
+    #define HAS_MICROSTEP8 1
+  #endif
+  #ifdef MICROSTEP16
+    #define HAS_MICROSTEP16 1
+  #endif
+  #ifdef MICROSTEP32
+    #define HAS_MICROSTEP32 1
+  #endif
+  #ifdef MICROSTEP64
+    #define HAS_MICROSTEP64 1
+  #endif
+  #ifdef MICROSTEP128
+    #define HAS_MICROSTEP128 1
+  #endif
 
 #endif // HAS_MICROSTEPS
 
@@ -1896,8 +2186,12 @@
   #undef NO_FAN_SLOWING_IN_PID_TUNING
 #endif
 
-#define QUIET_PROBING (HAS_BED_PROBE && (EITHER(PROBING_HEATERS_OFF, PROBING_FANS_OFF) || DELAY_BEFORE_PROBING > 0))
-#define HEATER_IDLE_HANDLER EITHER(ADVANCED_PAUSE_FEATURE, PROBING_HEATERS_OFF)
+#if HAS_BED_PROBE && (EITHER(PROBING_HEATERS_OFF, PROBING_FANS_OFF) || DELAY_BEFORE_PROBING > 0)
+  #define QUIET_PROBING 1
+#endif
+#if EITHER(ADVANCED_PAUSE_FEATURE, PROBING_HEATERS_OFF)
+  #define HEATER_IDLE_HANDLER 1
+#endif
 
 #if ENABLED(ADVANCED_PAUSE_FEATURE) && !defined(FILAMENT_CHANGE_SLOW_LOAD_LENGTH)
   #define FILAMENT_CHANGE_SLOW_LOAD_LENGTH 0
diff --git a/Marlin/src/inc/SanityCheck.h b/Marlin/src/inc/SanityCheck.h
index 1b2f7fd2fb..fd81f8e4f6 100644
--- a/Marlin/src/inc/SanityCheck.h
+++ b/Marlin/src/inc/SanityCheck.h
@@ -1591,11 +1591,11 @@ static_assert(Y_MAX_LENGTH >= Y_BED_SIZE, "Movement bounds (Y_MIN_POS, Y_MAX_POS
   #error "MAX6675_SS_PIN (required for TEMP_SENSOR_0) not defined for this board."
 #elif HOTENDS && !HAS_TEMP_HOTEND
   #error "TEMP_0_PIN (required for TEMP_SENSOR_0) not defined for this board."
-#elif (HOTENDS > 1 || ENABLED(HEATERS_PARALLEL)) && !HAS_HEATER_1
+#elif (HAS_MULTI_HOTEND || ENABLED(HEATERS_PARALLEL)) && !HAS_HEATER_1
   #error "HEATER_1_PIN not defined for this board."
 #endif
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #if ENABLED(HEATER_1_USES_MAX6675) && !PIN_EXISTS(MAX6675_SS2)
     #error "MAX6675_SS2_PIN (required for TEMP_SENSOR_1) not defined for this board."
   #elif TEMP_SENSOR_1 == 0
diff --git a/Marlin/src/lcd/HD44780/ultralcd_HD44780.cpp b/Marlin/src/lcd/HD44780/ultralcd_HD44780.cpp
index 3c89d1803c..905a72b053 100644
--- a/Marlin/src/lcd/HD44780/ultralcd_HD44780.cpp
+++ b/Marlin/src/lcd/HD44780/ultralcd_HD44780.cpp
@@ -745,7 +745,7 @@ void MarlinUI::draw_status_screen() {
       //
       // Hotend 1 or Bed Temperature
       //
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         lcd_moveto(8, 0);
         _draw_heater_status(H_E1, LCD_STR_THERMOMETER[0], blink);
       #elif HAS_HEATED_BED
@@ -763,7 +763,7 @@ void MarlinUI::draw_status_screen() {
       //
       // Hotend 1 or Bed Temperature
       //
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         lcd_moveto(10, 0);
         _draw_heater_status(H_E1, LCD_STR_THERMOMETER[0], blink);
       #elif HAS_HEATED_BED
@@ -791,7 +791,7 @@ void MarlinUI::draw_status_screen() {
         // If the first line has two extruder temps,
         // show more temperatures on the next line
 
-        #if HOTENDS > 2 || (HOTENDS > 1 && HAS_HEATED_BED)
+        #if HOTENDS > 2 || (HAS_MULTI_HOTEND && HAS_HEATED_BED)
 
           #if HOTENDS > 2
             _draw_heater_status(H_E2, LCD_STR_THERMOMETER[0], blink);
@@ -924,7 +924,7 @@ void MarlinUI::draw_status_screen() {
     lcd_moveto(LCD_WIDTH - 9, 0);
     _draw_axis_value(Z_AXIS, ftostr52sp(LOGICAL_Z_POSITION(current_position.z)), blink);
 
-    #if HAS_LEVELING && (HOTENDS > 1 || !HAS_HEATED_BED)
+    #if HAS_LEVELING && (HAS_MULTI_HOTEND || !HAS_HEATED_BED)
       lcd_put_wchar(LCD_WIDTH - 1, 0, planner.leveling_active || blink ? '_' : ' ');
     #endif
 
@@ -934,7 +934,7 @@ void MarlinUI::draw_status_screen() {
     // Hotend 1 or Bed Temperature
     //
     lcd_moveto(0, 1);
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       _draw_heater_status(H_E1, LCD_STR_THERMOMETER[0], blink);
     #elif HAS_HEATED_BED
       _draw_bed_status(blink);
@@ -952,7 +952,7 @@ void MarlinUI::draw_status_screen() {
     lcd_moveto(0, 2);
     #if HOTENDS > 2
       _draw_heater_status(H_E2, LCD_STR_THERMOMETER[0], blink);
-    #elif HOTENDS > 1 && HAS_HEATED_BED
+    #elif HAS_MULTI_HOTEND && HAS_HEATED_BED
       _draw_bed_status(blink);
     #elif HAS_PRINT_PROGRESS
       #define DREW_PRINT_PROGRESS
@@ -1077,7 +1077,7 @@ void MarlinUI::draw_status_screen() {
         if (thermalManager.degTargetBed() > 0) leds |= LED_A;
       #endif
 
-      #if HOTENDS
+      #if HAS_HOTEND
         if (thermalManager.degTargetHotend(0) > 0) leds |= LED_B;
       #endif
 
@@ -1110,7 +1110,7 @@ void MarlinUI::draw_status_screen() {
         ) leds |= LED_C;
       #endif // FAN_COUNT > 0
 
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         if (thermalManager.degTargetHotend(1) > 0) leds |= LED_C;
       #endif
 
diff --git a/Marlin/src/lcd/dogm/dogm_Statusscreen.h b/Marlin/src/lcd/dogm/dogm_Statusscreen.h
index 8295e9e058..741f07330f 100644
--- a/Marlin/src/lcd/dogm/dogm_Statusscreen.h
+++ b/Marlin/src/lcd/dogm/dogm_Statusscreen.h
@@ -278,7 +278,7 @@
     //
     // Status Screen Hotends bitmaps
     //
-    #if HOTENDS
+    #if HAS_HOTEND
 
       #define STATUS_HOTEND1_WIDTH  16
 
@@ -1343,7 +1343,7 @@
     #undef STATUS_LOGO_WIDTH
   #endif
 
-  #if (HOTENDS > 1 && STATUS_LOGO_WIDTH && BED_OR_CHAMBER_OR_FAN) || (HOTENDS >= 3 && !BED_OR_CHAMBER_OR_FAN)
+  #if (HAS_MULTI_HOTEND && STATUS_LOGO_WIDTH && BED_OR_CHAMBER_OR_FAN) || (HOTENDS >= 3 && !BED_OR_CHAMBER_OR_FAN)
     #define _STATUS_HEATERS_X(H,S,N) ((LCD_PIXEL_WIDTH - (H * (S + N)) - (_EXTRA_WIDTH) + (STATUS_LOGO_WIDTH)) / 2)
     #if STATUS_HOTEND1_WIDTH
       #if HOTENDS > 2
@@ -1474,7 +1474,7 @@
 
     constexpr uint8_t status_hotend_x[HOTENDS] = ARRAY_N(HOTENDS, STATUS_HOTEND1_X, STATUS_HOTEND2_X, STATUS_HOTEND3_X, STATUS_HOTEND4_X, STATUS_HOTEND5_X, STATUS_HOTEND6_X);
     #define STATUS_HOTEND_X(N) status_hotend_x[N]
-  #elif HOTENDS > 1
+  #elif HAS_MULTI_HOTEND
     #define STATUS_HOTEND_X(N) ((N) ? STATUS_HOTEND2_X : STATUS_HOTEND1_X)
   #else
     #define STATUS_HOTEND_X(N) STATUS_HOTEND1_X
diff --git a/Marlin/src/lcd/dogm/status_screen_lite_ST7920.cpp b/Marlin/src/lcd/dogm/status_screen_lite_ST7920.cpp
index e623776b31..64c6711fe8 100644
--- a/Marlin/src/lcd/dogm/status_screen_lite_ST7920.cpp
+++ b/Marlin/src/lcd/dogm/status_screen_lite_ST7920.cpp
@@ -431,7 +431,7 @@ void ST7920_Lite_Status_Screen::draw_static_elements() {
 
   // Draw the static icons in GDRAM
   draw_gdram_icon(0, 0, nozzle_icon);
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     draw_gdram_icon(0, 1, nozzle_icon);
     draw_gdram_icon(0, 2, bed_icon);
   #else
@@ -584,7 +584,7 @@ void ST7920_Lite_Status_Screen::draw_extruder_2_temp(const int16_t temp, const i
 #if HAS_HEATED_BED
   void ST7920_Lite_Status_Screen::draw_bed_temp(const int16_t temp, const int16_t target, bool forceUpdate) {
     const bool show_target = target && FAR(temp, target);
-    draw_temps(HOTENDS > 1 ? 2 : 1, temp, target, show_target, display_state.bed_show_target != show_target || forceUpdate);
+    draw_temps(HAS_MULTI_HOTEND ? 2 : 1, temp, target, show_target, display_state.bed_show_target != show_target || forceUpdate);
     display_state.bed_show_target = show_target;
   }
 #endif
@@ -704,7 +704,7 @@ bool ST7920_Lite_Status_Screen::indicators_changed() {
   const uint16_t   feedrate_perc     = feedrate_percentage;
   const uint16_t   fs                = thermalManager.scaledFanSpeed(0);
   const int16_t    extruder_1_target = thermalManager.degTargetHotend(0);
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     const int16_t  extruder_2_target = thermalManager.degTargetHotend(1);
   #endif
   #if HAS_HEATED_BED
@@ -731,7 +731,7 @@ void ST7920_Lite_Status_Screen::update_indicators(const bool forceUpdate) {
     const uint16_t   feedrate_perc     = feedrate_percentage;
     const int16_t    extruder_1_temp   = thermalManager.degHotend(0),
                      extruder_1_target = thermalManager.degTargetHotend(0);
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       const int16_t  extruder_2_temp   = thermalManager.degHotend(1),
                      extruder_2_target = thermalManager.degTargetHotend(1);
     #endif
@@ -741,7 +741,7 @@ void ST7920_Lite_Status_Screen::update_indicators(const bool forceUpdate) {
     #endif
 
     draw_extruder_1_temp(extruder_1_temp, extruder_1_target, forceUpdate);
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       draw_extruder_2_temp(extruder_2_temp, extruder_2_target, forceUpdate);
     #endif
     #if HAS_HEATED_BED
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/advanced_settings_menu.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/advanced_settings_menu.cpp
index c5f69504d4..e625325d44 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/advanced_settings_menu.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/advanced_settings_menu.cpp
@@ -115,7 +115,7 @@ void AdvancedSettingsMenu::onRedraw(draw_mode_t what) {
       )
       .tag(14).button( TMC_HOMING_THRS_POS,    GET_TEXT_F(MSG_TMC_HOMING_THRS))
       .enabled(
-        #if HOTENDS > 1
+        #if HAS_MULTI_HOTEND
           1
         #endif
       )
@@ -157,7 +157,7 @@ bool AdvancedSettingsMenu::onTouchEnd(uint8_t tag) {
     case 2:  GOTO_SCREEN(ZOffsetScreen);              break;
     #endif
     case 3:  GOTO_SCREEN(StepsScreen);                break;
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
     case 4:  GOTO_SCREEN(NozzleOffsetScreen);         break;
     #endif
     case 5:  GOTO_SCREEN(MaxVelocityScreen);          break;
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/bio_advanced_settings.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/bio_advanced_settings.cpp
index ed8bcee557..d2c5c6658c 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/bio_advanced_settings.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/bio_advanced_settings.cpp
@@ -58,7 +58,7 @@ void AdvancedSettingsMenu::onRedraw(draw_mode_t what) {
       .tag(4) .button( BTN_POS(1,3), BTN_SIZE(1,1), GET_TEXT_F(MSG_TMC_HOMING_THRS))
       .tag(5) .button( BTN_POS(1,4), BTN_SIZE(1,1), GET_TEXT_F(MSG_LCD_ENDSTOPS))
       .enabled(
-        #if HOTENDS > 1
+        #if HAS_MULTI_HOTEND
           1
         #endif
       )
@@ -105,7 +105,7 @@ bool AdvancedSettingsMenu::onTouchEnd(uint8_t tag) {
     case 4: GOTO_SCREEN(StepperBumpSensitivityScreen);     break;
     #endif
     case 5: GOTO_SCREEN(EndstopStatesScreen);              break;
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
     case 6: GOTO_SCREEN(NozzleOffsetScreen);               break;
     #endif
 
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/change_filament_screen.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/change_filament_screen.cpp
index 2b5963fdf6..a013949814 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/change_filament_screen.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/change_filament_screen.cpp
@@ -172,8 +172,8 @@ void ChangeFilamentScreen::onRedraw(draw_mode_t what) {
     const bool tog3  = screen_data.ChangeFilamentScreen.t_tag == 3;
     const bool tog4  = screen_data.ChangeFilamentScreen.t_tag == 4;
     const bool tog10 = screen_data.ChangeFilamentScreen.e_tag == 10;
-    #if HOTENDS > 1
-    const bool tog11 = screen_data.ChangeFilamentScreen.e_tag == 11;
+    #if HAS_MULTI_HOTEND
+      const bool tog11 = screen_data.ChangeFilamentScreen.e_tag == 11;
     #endif
 
     #ifdef TOUCH_UI_PORTRAIT
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nozzle_offsets_screen.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nozzle_offsets_screen.cpp
index ae224e9c11..9ac402e197 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nozzle_offsets_screen.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nozzle_offsets_screen.cpp
@@ -22,7 +22,7 @@
 
 #include "../config.h"
 
-#if ENABLED(TOUCH_UI_FTDI_EVE) && HOTENDS > 1
+#if ENABLED(TOUCH_UI_FTDI_EVE) && HAS_MULTI_HOTEND
 
 #include "screens.h"
 
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nudge_nozzle_screen.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nudge_nozzle_screen.cpp
index d9910ffa04..0865b8ccbc 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nudge_nozzle_screen.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/nudge_nozzle_screen.cpp
@@ -72,7 +72,7 @@ void NudgeNozzleScreen::onRedraw(draw_mode_t what) {
         w.text_field(0, GET_TEXT_F(MSG_ZPROBE_ZOFFSET), str);
       #endif
 
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         format_position(str, getNozzleOffset_mm(X, E1), getNozzleOffset_mm(Y, E1), getNozzleOffset_mm(Z, E1));
         w.text_field(0, GET_TEXT_F(MSG_OFFSETS_MENU), str);
       #endif
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.cpp
index 5f59843bbe..53d9d7a5ba 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.cpp
@@ -68,7 +68,7 @@ SCREEN_TABLE {
 #if HAS_BED_PROBE
   DECL_SCREEN(ZOffsetScreen),
 #endif
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   DECL_SCREEN(NozzleOffsetScreen),
 #endif
 #if ENABLED(BACKLASH_GCODE)
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.h b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.h
index 06f64d38cb..c659f50fc1 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.h
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/screens.h
@@ -514,7 +514,7 @@ class StepsScreen : public BaseNumericAdjustmentScreen, public CachedScreen<STEP
   };
 #endif
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   class NozzleOffsetScreen : public BaseNumericAdjustmentScreen, public CachedScreen<NOZZLE_OFFSET_SCREEN_CACHE> {
     public:
       static void onEntry();
diff --git a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/temperature_screen.cpp b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/temperature_screen.cpp
index 81cde5a341..4025d16bbd 100644
--- a/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/temperature_screen.cpp
+++ b/Marlin/src/lcd/extui/lib/ftdi_eve_touch_ui/screens/temperature_screen.cpp
@@ -78,7 +78,7 @@ bool TemperatureScreen::onTouchHeld(uint8_t tag) {
       case  2: UI_DECREMENT(TargetTemp_celsius, E0); break;
       case  3: UI_INCREMENT(TargetTemp_celsius, E0); break;
     #endif
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       case  4: UI_DECREMENT(TargetTemp_celsius, E1); break;
       case  5: UI_INCREMENT(TargetTemp_celsius, E1); break;
     #endif
diff --git a/Marlin/src/lcd/extui/ui_api.cpp b/Marlin/src/lcd/extui/ui_api.cpp
index b5f94539fe..55ae020616 100644
--- a/Marlin/src/lcd/extui/ui_api.cpp
+++ b/Marlin/src/lcd/extui/ui_api.cpp
@@ -192,7 +192,7 @@ namespace ExtUI {
           case CHAMBER: return; // Chamber has no idle timer
         #endif
         default:
-          #if HOTENDS
+          #if HAS_HOTEND
             thermalManager.reset_hotend_idle_timer(heater - H0);
           #endif
           break;
@@ -258,7 +258,7 @@ namespace ExtUI {
           case CHAMBER: return false; // Chamber has no idle timer
         #endif
         default:
-          #if HOTENDS
+          #if HAS_HOTEND
             return thermalManager.hotend_idle[heater - H0].timed_out;
           #else
             return false;
@@ -985,7 +985,7 @@ namespace ExtUI {
       else
     #endif
       {
-        #if HOTENDS
+        #if HAS_HOTEND
           static constexpr int16_t heater_maxtemp[HOTENDS] = ARRAY_BY_HOTENDS(HEATER_0_MAXTEMP, HEATER_1_MAXTEMP, HEATER_2_MAXTEMP, HEATER_3_MAXTEMP, HEATER_4_MAXTEMP, HEATER_5_MAXTEMP, HEATER_6_MAXTEMP, HEATER_7_MAXTEMP);
           const int16_t e = heater - H0;
           thermalManager.setTargetHotend(LROUND(constrain(value, 0, heater_maxtemp[e] - 15)), e);
@@ -997,7 +997,7 @@ namespace ExtUI {
     #ifdef TOUCH_UI_LCD_TEMP_SCALING
       value *= TOUCH_UI_LCD_TEMP_SCALING;
     #endif
-    #if HOTENDS
+    #if HAS_HOTEND
       constexpr int16_t heater_maxtemp[HOTENDS] = ARRAY_BY_HOTENDS(HEATER_0_MAXTEMP, HEATER_1_MAXTEMP, HEATER_2_MAXTEMP, HEATER_3_MAXTEMP, HEATER_4_MAXTEMP, HEATER_5_MAXTEMP, HEATER_6_MAXTEMP, HEATER_7_MAXTEMP);
       const int16_t e = extruder - E0;
       enableHeater(extruder);
diff --git a/Marlin/src/lcd/menu/menu.h b/Marlin/src/lcd/menu/menu.h
index 5d4b655167..5f3e6d965a 100644
--- a/Marlin/src/lcd/menu/menu.h
+++ b/Marlin/src/lcd/menu/menu.h
@@ -29,7 +29,7 @@
 
 extern int8_t encoderLine, encoderTopLine, screen_items;
 
-#if HOTENDS
+#if HAS_HOTEND
   constexpr int16_t heater_maxtemp[HOTENDS] = ARRAY_BY_HOTENDS(HEATER_0_MAXTEMP, HEATER_1_MAXTEMP, HEATER_2_MAXTEMP, HEATER_3_MAXTEMP, HEATER_4_MAXTEMP, HEATER_5_MAXTEMP, HEATER_6_MAXTEMP, HEATER_7_MAXTEMP);
 #endif
 
diff --git a/Marlin/src/lcd/menu/menu_advanced.cpp b/Marlin/src/lcd/menu/menu_advanced.cpp
index ac755af7c4..f0bbfdfed1 100644
--- a/Marlin/src/lcd/menu/menu_advanced.cpp
+++ b/Marlin/src/lcd/menu/menu_advanced.cpp
@@ -233,9 +233,9 @@ void menu_cancelobject();
   #define DEFINE_PIDTEMP_FUNCS(N) _DEFINE_PIDTEMP_BASE_FUNCS(N);
 #endif
 
-#if HOTENDS
+#if HAS_HOTEND
   DEFINE_PIDTEMP_FUNCS(0);
-  #if HOTENDS > 1 && ENABLED(PID_PARAMS_PER_HOTEND)
+  #if HAS_MULTI_HOTEND && ENABLED(PID_PARAMS_PER_HOTEND)
     REPEAT_S(1, HOTENDS, DEFINE_PIDTEMP_FUNCS)
   #endif
 #endif
@@ -308,7 +308,7 @@ void menu_cancelobject();
     #endif
 
     PID_EDIT_MENU_ITEMS(0);
-    #if HOTENDS > 1 && ENABLED(PID_PARAMS_PER_HOTEND)
+    #if HAS_MULTI_HOTEND && ENABLED(PID_PARAMS_PER_HOTEND)
       REPEAT_S(1, HOTENDS, PID_EDIT_MENU_ITEMS)
     #endif
 
diff --git a/Marlin/src/lcd/menu/menu_temperature.cpp b/Marlin/src/lcd/menu/menu_temperature.cpp
index b00a3d964a..5229093fd6 100644
--- a/Marlin/src/lcd/menu/menu_temperature.cpp
+++ b/Marlin/src/lcd/menu/menu_temperature.cpp
@@ -48,7 +48,7 @@ uint8_t MarlinUI::preheat_fan_speed[2];
 //
 
 void _lcd_preheat(const int16_t endnum, const int16_t temph, const int16_t tempb, const uint8_t fan) {
-  #if HOTENDS
+  #if HAS_HOTEND
     if (temph > 0) thermalManager.setTargetHotend(_MIN(heater_maxtemp[endnum] - 15, temph), endnum);
   #endif
   #if HAS_HEATED_BED
@@ -107,7 +107,7 @@ void _lcd_preheat(const int16_t endnum, const int16_t temph, const int16_t tempb
       #else
         ACTION_ITEM(MSG_PREHEAT_1, []{ _preheat_end(0, 0); });
       #endif
-    #elif HOTENDS > 1
+    #elif HAS_MULTI_HOTEND
       #if HAS_HEATED_BED
         _PREHEAT_ITEMS(1,0);
       #endif
@@ -118,7 +118,7 @@ void _lcd_preheat(const int16_t endnum, const int16_t temph, const int16_t tempb
         #endif
         HOTEND_LOOP() thermalManager.setTargetHotend(ui.preheat_hotend_temp[0], e);
       });
-    #endif // HOTENDS > 1
+    #endif // HAS_MULTI_HOTEND
     #if HAS_HEATED_BED
       ACTION_ITEM(MSG_PREHEAT_1_BEDONLY, []{ _preheat_bed(0); });
     #endif
@@ -135,7 +135,7 @@ void _lcd_preheat(const int16_t endnum, const int16_t temph, const int16_t tempb
       #else
         ACTION_ITEM(MSG_PREHEAT_2, []{ _preheat_end(1, 0); });
       #endif
-    #elif HOTENDS > 1
+    #elif HAS_MULTI_HOTEND
       #if HAS_HEATED_BED
         _PREHEAT_ITEMS(2,0);
       #endif
@@ -146,7 +146,7 @@ void _lcd_preheat(const int16_t endnum, const int16_t temph, const int16_t tempb
         #endif
         HOTEND_LOOP() thermalManager.setTargetHotend(ui.preheat_hotend_temp[1], e);
       });
-    #endif // HOTENDS > 1
+    #endif // HAS_MULTI_HOTEND
     #if HAS_HEATED_BED
       ACTION_ITEM(MSG_PREHEAT_2_BEDONLY, []{ _preheat_bed(1); });
     #endif
@@ -171,7 +171,7 @@ void menu_temperature() {
   //
   #if HOTENDS == 1
     EDIT_ITEM_FAST(int3, MSG_NOZZLE, &thermalManager.temp_hotend[0].target, 0, HEATER_0_MAXTEMP - 15, []{ thermalManager.start_watching_hotend(0); });
-  #elif HOTENDS > 1
+  #elif HAS_MULTI_HOTEND
     HOTEND_LOOP()
       EDIT_ITEM_FAST_N(int3, e, MSG_NOZZLE_N, &thermalManager.temp_hotend[e].target, 0, heater_maxtemp[e] - 15, []{ thermalManager.start_watching_hotend(MenuItemBase::itemIndex); });
   #endif
diff --git a/Marlin/src/lcd/menu/menu_tune.cpp b/Marlin/src/lcd/menu/menu_tune.cpp
index ac18e89df4..a36f6afc90 100644
--- a/Marlin/src/lcd/menu/menu_tune.cpp
+++ b/Marlin/src/lcd/menu/menu_tune.cpp
@@ -127,7 +127,7 @@ void menu_tune() {
   //
   #if HOTENDS == 1
     EDIT_ITEM_FAST(int3, MSG_NOZZLE, &thermalManager.temp_hotend[0].target, 0, HEATER_0_MAXTEMP - 15, []{ thermalManager.start_watching_hotend(0); });
-  #elif HOTENDS > 1
+  #elif HAS_MULTI_HOTEND
     HOTEND_LOOP()
       EDIT_ITEM_FAST_N(int3, e, MSG_NOZZLE_N, &thermalManager.temp_hotend[e].target, 0, heater_maxtemp[e] - 15, []{ thermalManager.start_watching_hotend(MenuItemBase::itemIndex); });
   #endif
diff --git a/Marlin/src/module/configuration_store.cpp b/Marlin/src/module/configuration_store.cpp
index 0211c303eb..cdc4432a53 100644
--- a/Marlin/src/module/configuration_store.cpp
+++ b/Marlin/src/module/configuration_store.cpp
@@ -3194,7 +3194,7 @@ void MarlinSettings::reset() {
         HOTEND_LOOP() {
           CONFIG_ECHO_START();
           SERIAL_ECHOPAIR_P(
-            #if HOTENDS > 1 && ENABLED(PID_PARAMS_PER_HOTEND)
+            #if HAS_MULTI_HOTEND && ENABLED(PID_PARAMS_PER_HOTEND)
               PSTR("  M301 E"), e,
               SP_P_STR
             #else
diff --git a/Marlin/src/module/temperature.cpp b/Marlin/src/module/temperature.cpp
index 650cda51f3..0ca7535ec7 100644
--- a/Marlin/src/module/temperature.cpp
+++ b/Marlin/src/module/temperature.cpp
@@ -140,7 +140,7 @@ const char str_t_thermal_runaway[] PROGMEM = STR_T_THERMAL_RUNAWAY,
   bool Temperature::adaptive_fan_slowing = true;
 #endif
 
-#if HOTENDS
+#if HAS_HOTEND
   hotend_info_t Temperature::temp_hotend[HOTEND_TEMPS]; // = { 0 }
 #endif
 
@@ -298,7 +298,7 @@ volatile bool Temperature::raw_temps_ready = false;
 
 #define TEMPDIR(N) ((HEATER_##N##_RAW_LO_TEMP) < (HEATER_##N##_RAW_HI_TEMP) ? 1 : -1)
 
-#if HOTENDS
+#if HAS_HOTEND
   // Init mintemp and maxtemp with extreme values to prevent false errors during startup
   constexpr temp_range_t sensor_heater_0 { HEATER_0_RAW_LO_TEMP, HEATER_0_RAW_HI_TEMP, 0, 16383 },
                          sensor_heater_1 { HEATER_1_RAW_LO_TEMP, HEATER_1_RAW_HI_TEMP, 0, 16383 },
@@ -655,7 +655,7 @@ int16_t Temperature::getHeaterPower(const heater_ind_t heater_id) {
     #endif
     default:
       return (0
-        #if HOTENDS
+        #if HAS_HOTEND
           + temp_hotend[heater_id].soft_pwm_amount
         #endif
       );
@@ -672,7 +672,7 @@ int16_t Temperature::getHeaterPower(const heater_ind_t heater_id) {
     #define _EFAN(B,A) _EFANOVERLAP(A,B) ? B :
     static const uint8_t fanBit[] PROGMEM = {
       0
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         #define _NEXT_FAN(N) , REPEAT2(N,_EFAN,N) N
         RREPEAT_S(1, HOTENDS, _NEXT_FAN)
       #endif
@@ -821,7 +821,7 @@ void Temperature::min_temp_error(const heater_ind_t heater) {
   _temp_error(heater, PSTR(STR_T_MINTEMP), GET_TEXT(MSG_ERR_MINTEMP));
 }
 
-#if HOTENDS
+#if HAS_HOTEND
   #if ENABLED(PID_DEBUG)
     extern bool pid_debug_flag;
   #endif
@@ -1036,7 +1036,7 @@ void Temperature::manage_heater() {
 
   millis_t ms = millis();
 
-  #if HOTENDS
+  #if HAS_HOTEND
 
     HOTEND_LOOP() {
       #if ENABLED(THERMAL_PROTECTION_HOTENDS)
@@ -1384,7 +1384,7 @@ void Temperature::manage_heater() {
   }
 #endif
 
-#if HOTENDS
+#if HAS_HOTEND
   // Derived from RepRap FiveD extruder::getTemperature()
   // For hot end temperature measurement.
   float Temperature::analog_to_celsius_hotend(const int raw, const uint8_t e) {
@@ -1575,7 +1575,7 @@ void Temperature::updateTemperaturesFromRawValues() {
   #if ENABLED(HEATER_1_USES_MAX6675)
     temp_hotend[1].raw = READ_MAX6675(1);
   #endif
-  #if HOTENDS
+  #if HAS_HOTEND
     HOTEND_LOOP() temp_hotend[e].celsius = analog_to_celsius_hotend(temp_hotend[e].raw, e);
   #endif
   #if HAS_HEATED_BED
@@ -1836,7 +1836,7 @@ void Temperature::init() {
   // Wait for temperature measurement to settle
   delay(250);
 
-  #if HOTENDS
+  #if HAS_HOTEND
 
     #define _TEMP_MIN_E(NR) do{ \
       temp_range[NR].mintemp = HEATER_ ##NR## _MINTEMP; \
@@ -1855,7 +1855,7 @@ void Temperature::init() {
     #ifdef HEATER_0_MAXTEMP
       _TEMP_MAX_E(0);
     #endif
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       #ifdef HEATER_1_MINTEMP
         _TEMP_MIN_E(1);
       #endif
@@ -1910,7 +1910,7 @@ void Temperature::init() {
           #endif // HOTENDS > 4
         #endif // HOTENDS > 3
       #endif // HOTENDS > 2
-    #endif // HOTENDS > 1
+    #endif // HAS_MULTI_HOTEND
 
   #endif // HOTENDS
 
@@ -2070,7 +2070,7 @@ void Temperature::disable_all_heaters() {
     planner.autotemp_enabled = false;
   #endif
 
-  #if HOTENDS
+  #if HAS_HOTEND
     HOTEND_LOOP() setTargetHotend(0, e);
   #endif
 
@@ -2113,7 +2113,7 @@ void Temperature::disable_all_heaters() {
 #if ENABLED(PRINTJOB_TIMER_AUTOSTART)
 
   bool Temperature::over_autostart_threshold() {
-    #if HOTENDS
+    #if HAS_HOTEND
       HOTEND_LOOP() if (degTargetHotend(e) > (EXTRUDE_MINTEMP) / 2) return true;
     #endif
     #if HAS_HEATED_BED
@@ -2358,7 +2358,7 @@ void Temperature::readings_ready() {
     filwidth.reading_ready();
   #endif
 
-  #if HOTENDS
+  #if HAS_HOTEND
     HOTEND_LOOP() temp_hotend[e].reset();
     #if ENABLED(TEMP_SENSOR_1_AS_REDUNDANT)
       temp_hotend[1].reset();
@@ -2387,7 +2387,7 @@ void Temperature::readings_ready() {
     joystick.z.reset();
   #endif
 
-  #if HOTENDS
+  #if HAS_HOTEND
 
     static constexpr int8_t temp_dir[] = {
       #if ENABLED(HEATER_0_USES_MAX6675)
@@ -2395,7 +2395,7 @@ void Temperature::readings_ready() {
       #else
         TEMPDIR(0)
       #endif
-      #if HOTENDS > 1
+      #if HAS_MULTI_HOTEND
         #define _TEMPDIR(N) , TEMPDIR(N)
         #if ENABLED(HEATER_1_USES_MAX6675)
           , 0
@@ -2405,7 +2405,7 @@ void Temperature::readings_ready() {
         #if HOTENDS > 2
           REPEAT_S(2, HOTENDS, _TEMPDIR)
         #endif // HOTENDS > 2
-      #endif // HOTENDS > 1
+      #endif // HAS_MULTI_HOTEND
     };
 
     LOOP_L_N(e, COUNT(temp_dir)) {
@@ -2531,7 +2531,7 @@ void Temperature::tick() {
     static bool ADCKey_pressed = false;
   #endif
 
-  #if HOTENDS
+  #if HAS_HOTEND
     static SoftPWM soft_pwm_hotend[HOTENDS];
   #endif
 
@@ -2565,7 +2565,7 @@ void Temperature::tick() {
     if (pwm_count_tmp >= 127) {
       pwm_count_tmp -= 127;
 
-      #if HOTENDS
+      #if HAS_HOTEND
         #define _PWM_MOD_E(N) _PWM_MOD(N,soft_pwm_hotend[N],temp_hotend[N]);
         REPEAT(HOTENDS, _PWM_MOD_E);
       #endif
@@ -2612,7 +2612,7 @@ void Temperature::tick() {
     }
     else {
       #define _PWM_LOW(N,S) do{ if (S.count <= pwm_count_tmp) WRITE_HEATER_##N(LOW); }while(0)
-      #if HOTENDS
+      #if HAS_HOTEND
         #define _PWM_LOW_E(N) _PWM_LOW(N, soft_pwm_hotend[N]);
         REPEAT(HOTENDS, _PWM_LOW_E);
       #endif
@@ -2678,7 +2678,7 @@ void Temperature::tick() {
 
     if (slow_pwm_count == 0) {
 
-      #if HOTENDS
+      #if HAS_HOTEND
         #define _SLOW_PWM_E(N) _SLOW_PWM(N, soft_pwm_hotend[N], temp_hotend[N]);
         REPEAT(HOTENDS, _SLOW_PWM_E);
       #endif
@@ -2689,7 +2689,7 @@ void Temperature::tick() {
 
     } // slow_pwm_count == 0
 
-    #if HOTENDS
+    #if HAS_HOTEND
       #define _PWM_OFF_E(N) _PWM_OFF(N, soft_pwm_hotend[N]);
       REPEAT(HOTENDS, _PWM_OFF_E);
     #endif
@@ -2772,7 +2772,7 @@ void Temperature::tick() {
       slow_pwm_count++;
       slow_pwm_count &= 0x7F;
 
-      #if HOTENDS
+      #if HAS_HOTEND
         HOTEND_LOOP() soft_pwm_hotend[e].dec();
       #endif
       #if HAS_HEATED_BED
@@ -2990,7 +2990,7 @@ void Temperature::tick() {
     }
     SERIAL_CHAR(' ');
     SERIAL_CHAR(k);
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       if (e >= 0) SERIAL_CHAR('0' + e);
     #endif
     SERIAL_CHAR(':');
@@ -3052,7 +3052,7 @@ void Temperature::tick() {
         , H_PROBE
       );
     #endif // HAS_TEMP_PROBE
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       HOTEND_LOOP() print_heater_state(degHotend(e), degTargetHotend(e)
         #if ENABLED(SHOW_TEMP_ADC_VALUES)
           , rawHotendTemp(e)
@@ -3067,7 +3067,7 @@ void Temperature::tick() {
     #if HAS_HEATED_CHAMBER
       SERIAL_ECHOPAIR(" C@:", getHeaterPower(H_CHAMBER));
     #endif
-    #if HOTENDS > 1
+    #if HAS_MULTI_HOTEND
       HOTEND_LOOP() {
         SERIAL_ECHOPAIR(" @", e);
         SERIAL_CHAR(':');
@@ -3096,7 +3096,7 @@ void Temperature::tick() {
     void Temperature::set_heating_message(const uint8_t e) {
       const bool heating = isHeatingHotend(e);
       ui.status_printf_P(0,
-        #if HOTENDS > 1
+        #if HAS_MULTI_HOTEND
           PSTR("E%c " S_FMT), '1' + e
         #else
           PSTR("E " S_FMT)
diff --git a/Marlin/src/module/temperature.h b/Marlin/src/module/temperature.h
index cba1642afd..981615c1b4 100644
--- a/Marlin/src/module/temperature.h
+++ b/Marlin/src/module/temperature.h
@@ -317,12 +317,12 @@ class Temperature {
 
   public:
 
-    #if HOTENDS
       #if ENABLED(TEMP_SENSOR_1_AS_REDUNDANT)
         #define HOTEND_TEMPS (HOTENDS + 1)
       #else
         #define HOTEND_TEMPS HOTENDS
       #endif
+    #if HAS_HOTEND
       static hotend_info_t temp_hotend[HOTEND_TEMPS];
     #endif
     #if HAS_HEATED_BED
@@ -496,7 +496,7 @@ class Temperature {
       }
     #endif
 
-    #if HOTENDS
+    #if HAS_HOTEND
       static float analog_to_celsius_hotend(const int raw, const uint8_t e);
     #endif
 
@@ -624,7 +624,7 @@ class Temperature {
       static inline void start_watching_hotend(const uint8_t=0) {}
     #endif
 
-    #if HOTENDS
+    #if HAS_HOTEND
 
       static void setTargetHotend(const int16_t celsius, const uint8_t E_NAME) {
         const uint8_t ee = HOTEND_INDEX;
diff --git a/Marlin/src/pins/linux/pins_RAMPS_LINUX.h b/Marlin/src/pins/linux/pins_RAMPS_LINUX.h
index 0bfbaabdcd..27d9bc11cc 100644
--- a/Marlin/src/pins/linux/pins_RAMPS_LINUX.h
+++ b/Marlin/src/pins/linux/pins_RAMPS_LINUX.h
@@ -142,7 +142,7 @@
 // Augmentation for auto-assigning RAMPS plugs
 //
 #if NONE(IS_RAMPS_EEB, IS_RAMPS_EEF, IS_RAMPS_EFB, IS_RAMPS_EFF, IS_RAMPS_SF) && !PIN_EXISTS(MOSFET_D)
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if TEMP_SENSOR_BED
       #define IS_RAMPS_EEB
     #else
diff --git a/Marlin/src/pins/lpc1768/pins_RAMPS_RE_ARM.h b/Marlin/src/pins/lpc1768/pins_RAMPS_RE_ARM.h
index b8b04a348c..52dd9b2eb5 100644
--- a/Marlin/src/pins/lpc1768/pins_RAMPS_RE_ARM.h
+++ b/Marlin/src/pins/lpc1768/pins_RAMPS_RE_ARM.h
@@ -184,7 +184,7 @@
 // Augmentation for auto-assigning RAMPS plugs
 //
 #if NONE(IS_RAMPS_EEB, IS_RAMPS_EEF, IS_RAMPS_EFB, IS_RAMPS_EFF, IS_RAMPS_SF) && !PIN_EXISTS(MOSFET_D)
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if TEMP_SENSOR_BED
       #define IS_RAMPS_EEB
     #else
diff --git a/Marlin/src/pins/mega/pins_MIGHTYBOARD_REVE.h b/Marlin/src/pins/mega/pins_MIGHTYBOARD_REVE.h
index 3282216819..f3d338aa2a 100644
--- a/Marlin/src/pins/mega/pins_MIGHTYBOARD_REVE.h
+++ b/Marlin/src/pins/mega/pins_MIGHTYBOARD_REVE.h
@@ -159,7 +159,7 @@
 #define HBP_PIN                               45  // L4
 #define EXTRA_FET_PIN                         44  // L5
 
-#if HOTENDS > 1
+#if HAS_MULTI_HOTEND
   #if TEMP_SENSOR_BED
     #define IS_EEB
   #else
diff --git a/Marlin/src/pins/ramps/pins_FORMBOT_RAPTOR.h b/Marlin/src/pins/ramps/pins_FORMBOT_RAPTOR.h
index 75d647fed5..8993d0ff57 100644
--- a/Marlin/src/pins/ramps/pins_FORMBOT_RAPTOR.h
+++ b/Marlin/src/pins/ramps/pins_FORMBOT_RAPTOR.h
@@ -124,7 +124,7 @@
 // Augmentation for auto-assigning RAMPS plugs
 //
 #if NONE(IS_RAMPS_EEB, IS_RAMPS_EEF, IS_RAMPS_EFB, IS_RAMPS_EFF, IS_RAMPS_SF) && !PIN_EXISTS(MOSFET_D)
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if TEMP_SENSOR_BED
       #define IS_RAMPS_EEB
     #else
diff --git a/Marlin/src/pins/ramps/pins_FORMBOT_TREX2PLUS.h b/Marlin/src/pins/ramps/pins_FORMBOT_TREX2PLUS.h
index 5176c699ee..4e62c67aaf 100644
--- a/Marlin/src/pins/ramps/pins_FORMBOT_TREX2PLUS.h
+++ b/Marlin/src/pins/ramps/pins_FORMBOT_TREX2PLUS.h
@@ -130,7 +130,7 @@
 // Augmentation for auto-assigning RAMPS plugs
 //
 #if NONE(IS_RAMPS_EEB, IS_RAMPS_EEF, IS_RAMPS_EFB, IS_RAMPS_EFF, IS_RAMPS_SF) && !PIN_EXISTS(MOSFET_D)
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if TEMP_SENSOR_BED
       #define IS_RAMPS_EEB
     #else
diff --git a/Marlin/src/pins/ramps/pins_RAMPS.h b/Marlin/src/pins/ramps/pins_RAMPS.h
index ffe7f7bb1e..be3f33ebfd 100644
--- a/Marlin/src/pins/ramps/pins_RAMPS.h
+++ b/Marlin/src/pins/ramps/pins_RAMPS.h
@@ -180,7 +180,7 @@
 // Augmentation for auto-assigning RAMPS plugs
 //
 #if NONE(IS_RAMPS_EEB, IS_RAMPS_EEF, IS_RAMPS_EFB, IS_RAMPS_EFF, IS_RAMPS_SF) && !PIN_EXISTS(MOSFET_D)
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #if TEMP_SENSOR_BED
       #define IS_RAMPS_EEB
     #else
diff --git a/Marlin/src/pins/ramps/pins_TRIGORILLA_14.h b/Marlin/src/pins/ramps/pins_TRIGORILLA_14.h
index adbacfbf4d..cfb9acb054 100644
--- a/Marlin/src/pins/ramps/pins_TRIGORILLA_14.h
+++ b/Marlin/src/pins/ramps/pins_TRIGORILLA_14.h
@@ -59,7 +59,7 @@
 
 #define RAMPS_D10_PIN            TG_HEATER_0_PIN  // HEATER_0_PIN is always RAMPS_D10_PIN in pins_RAMPS.h
 
-#if HOTENDS > 1                                   // EEF and EEB
+#if HAS_MULTI_HOTEND                                   // EEF and EEB
   #define RAMPS_D9_PIN           TG_HEATER_1_PIN
   #if !TEMP_SENSOR_BED
     // EEF
@@ -79,7 +79,7 @@
   #define RAMPS_D8_PIN               TG_FAN0_PIN
 #endif
 
-#if HOTENDS > 1 || TEMP_SENSOR_BED                // EEF, EEB, EFB
+#if HAS_MULTI_HOTEND || TEMP_SENSOR_BED                // EEF, EEB, EFB
   #define FAN1_PIN                   TG_FAN1_PIN
 #endif
 #define FAN2_PIN                     TG_FAN2_PIN
diff --git a/Marlin/src/pins/sensitive_pins.h b/Marlin/src/pins/sensitive_pins.h
index 12cadcbd9c..9ca5aa1ee2 100644
--- a/Marlin/src/pins/sensitive_pins.h
+++ b/Marlin/src/pins/sensitive_pins.h
@@ -423,10 +423,10 @@
 #define _H6_PINS
 #define _H7_PINS
 
-#if HOTENDS
+#if HAS_HOTEND
   #undef _H0_PINS
   #define _H0_PINS HEATER_0_PIN, E0_AUTO_FAN_PIN, analogInputToDigitalPin(TEMP_0_PIN),
-  #if HOTENDS > 1
+  #if HAS_MULTI_HOTEND
     #undef _H1_PINS
     #define _H1_PINS HEATER_1_PIN, E1_AUTO_FAN_PIN, analogInputToDigitalPin(TEMP_1_PIN),
     #if HOTENDS > 2
@@ -453,7 +453,7 @@
         #endif // HOTENDS > 4
       #endif // HOTENDS > 3
     #endif // HOTENDS > 2
-  #endif // HOTENDS > 1
+  #endif // HAS_MULTI_HOTEND
 #endif // HOTENDS
 
 //